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Massachusetts Institute of Technology (MIT) is a private research university in Cambridge, Massachusetts. The institute is a land-grant, sea-grant, and space-grant university, with an urban campus that extends more than a mile (1.6 km) alongside the Charles River. The institute also encompasses a number of major off-campus facilities such as the MIT Lincoln Laboratory, the Bates Center, and the Haystack Observatory, as well as affiliated laboratories such as the Broad and Whitehead Institutes. Founded in 1861 in response to the increasing industrialization of the United States, MIT adopted a European polytechnic university model and stressed laboratory instruction in applied science and engineering. It has since played a key role in the development of many aspects of modern science, engineering, mathematics, and technology, and is widely known for its innovation and academic strength.

Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Established in 1636 and named for its first benefactor, clergyman John Harvard, Harvard is the oldest institution of higher learning in the United States and among the most prestigious in the world.

The Massachusetts colonial legislature, the General Court, authorized Harvard’s founding. In its early years, Harvard College primarily trained Congregational and Unitarian clergy, although it has never been formally affiliated with any denomination. Its curriculum and student body were gradually secularized during the 18th century, and by the 19th century, Harvard had emerged as the central cultural establishment among Boston elites. Following the American Civil War, President Charles William Eliot’s long tenure (1869–1909) transformed the college and affiliated professional schools into a modern research university; Harvard became a founding member of the Association of American Universities in 1900. James B. Conant led the university through the Great Depression and World War II; he liberalized admissions after the war.

Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. Stanford is considered one of the most prestigious universities in the world by numerous major education publications.

The university was founded in 1885 by Leland and Jane Stanford in memory of their only child, Leland Stanford Jr., who had died of typhoid fever at age 15 the previous year. Stanford was a U.S. Senator and former Governor of California who made his fortune as a railroad tycoon. The school admitted its first students on October 1, 1891, as a coeducational and non-denominational institution.

Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private Ivy League research university in New York City. Established in 1754 on the grounds of Trinity Church in Manhattan, Columbia is the oldest institution of higher education in New York and the fifth-oldest institution of higher learning in the United States. It is one of nine colonial colleges founded prior to the Declaration of Independence, seven of which belong to the Ivy League. Columbia has been ranked among the most prestigious universities in the world by numerous major education publications.

Boston University (BU) is a private research university in Boston, Massachusetts. The university is nonsectarian, but maintains its historical affiliation with the United Methodist Church. It was founded in 1839 by Methodists with its original campus in Newbury, Vermont, before moving to Boston in 1867. The university now has over 3,900 faculty members and nearly 33,000 students, and is one of Boston’s largest employers. It offers bachelor’s degrees, master’s degrees, doctorates, and medical, dental, business, and law degrees through 18 schools and colleges on two urban campuses. The main campus is situated along the Charles River in Boston’s Fenway-Kenmore and Allston neighborhoods, while the Boston University Medical Campus is located in Boston’s South End neighborhood.

Fordham University is a private research university in New York City, United States. Established in 1841 and named for the Fordham neighborhood of the Bronx in which its original campus is located, Fordham is the oldest Catholic and Jesuit university in the northeastern United States, and the third-oldest university in New York State.

Founded as St. John’s College by John Hughes, then a coadjutor bishop of New York, the college was placed in the care of the Society of Jesus shortly thereafter, and has since become a Jesuit-affiliated independent school under a lay board of trustees. The college’s first president, John McCloskey, was later the first Catholic cardinal in the United States. While governed independently of the Church since 1969, every president of Fordham University since 1846 has been a Jesuit priest, and the curriculum remains influenced by Jesuit educational principles. Fordham is the only Jesuit tertiary institution in New York City.